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Industry Insight
The biology of roginolisib: Activity without immune toxicity
Industry Insight
End of year reflections from our CEO
Industry Insight
Driving breakthroughs for myelofibrosis care
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What’s next for cambritaxestat?
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Realizing the potential of PI3Kδ inhibitors in peripheral T-cell lymphomas
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iOnctura expands roginolisib trials to the US
Industry Insight
iOnctura enhances board to accelerate growth and innovation
Industry Insight
Addressing drug resistance in non-small cell lung cancer
Industry Insight
Scientific innovation in uveal melanoma
Industry Insight
Opportunities and challenges in oncology immunotherapy
Industry Insight
Reflections from our CEO
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Pancreatic cancer – our commitment to scientific advances
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A bold new era in global cancer drug discovery
Industry Insight
A note from our CEO
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Realising the potential of autotaxin therapy in cancer
Industry Insight
PI3Kδ inhibitors offer serious promise in solid tumors
Industry Insight
Emerging therapies offer hope for uveal melanoma patients
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Data & publication
The PI3Kδ inhibitor roginolisib (IOA-244) preserves T-cell function and activity
Press release
iOnctura CEO to present at the 2026 J.P. Morgan Healthcare Conference
Data & publication
The selective PI3Kδ inhibitor roginolisib synergizes with ruxolitinib against progenitor cells from naïve and JAKi-refractory/resistant patients with myelofibrosis
Data & publication
Roginolisib (IOA-244), an orally bioavailable, selective PI3Kδ inhibitor, in combination with venetoclax and rituximab in patients with relapsed chronic lymphocytic leukemia (CLL)
Data & publication
PlaΤform: A multicenter, multi-arm, academic platform trial evaluating novel agents and combinations in relapsed or refractory peripheral T-cell lymphomas
Data & publication
Trial in progress: A study of roginolisib in combination with ruxolitinib in patients with myelofibrosis who are unresponsive to JAK inhibitors (HEMA-MED)
Press coverage
Drug Discovery World – ASH 2025: Combined focus on myelofibrosis
Press release
iOnctura initiates Phase I/II trial in patients with myelofibrosis ahead of new non-clinical data at ASH
Data & publication
The PI3Kδ inhibitor roginolisib (IOA-244) preserves T cell function and activity
Press release
iOnctura Expands Roginolisib Trials to the US, Advancing Multi-Indication Strategy in Oncology
Press coverage
OncLive – Early Activity With Roginolisib Supports Ongoing Phase 2 OCULE-01 Trial in Metastatic Uveal Melanoma
Data & publication
Novel PI3kδ inhibitor roginolisib synergizes with venetoclax in hematologic malignancies
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