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Industry Insight
End of year reflections from our CEO
Industry Insight
Driving breakthroughs for myelofibrosis care
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What’s next for cambritaxestat?
Industry Insight
Realizing the potential of PI3Kδ inhibitors in peripheral T-cell lymphomas
Industry Insight
iOnctura expands roginolisib trials to the US
Industry Insight
iOnctura enhances board to accelerate growth and innovation
Industry Insight
Addressing drug resistance in non-small cell lung cancer
Industry Insight
Scientific innovation in uveal melanoma
Industry Insight
Opportunities and challenges in oncology immunotherapy
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Reflections from our CEO
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Pancreatic cancer – our commitment to scientific advances
Industry Insight
A bold new era in global cancer drug discovery
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Data & publication
The selective PI3Kδ inhibitor roginolisib synergizes with ruxolitinib against progenitor cells from naïve and JAKi-refractory/resistant patients with myelofibrosis
Data & publication
Roginolisib (IOA-244), an orally bioavailable, selective PI3Kδ inhibitor, in combination with venetoclax and rituximab in patients with relapsed chronic lymphocytic leukemia (CLL)
Data & publication
PlaΤform: A multicenter, multi-arm, academic platform trial evaluating novel agents and combinations in relapsed or refractory peripheral T-cell lymphomas
Data & publication
Trial in progress: A study of roginolisib in combination with ruxolitinib in patients with myelofibrosis who are unresponsive to JAK inhibitors (HEMA-MED)
Press coverage
Drug Discovery World: ASH 2025: Combined focus on myelofibrosis
Press release
iOnctura initiates Phase I/II trial in patients with myelofibrosis ahead of new non-clinical data at ASH
Data & publication
Safety and clinical efficacy of cambritaxestat (IOA-289), a novel autotaxin inhibitor, plus gemcitabine and nab-paclitaxel (GnP) in patients with previously untreated metastatic pancreatic ductal adenocarcinoma (mPDAC)
Press release
iOnctura debuts cambritaxestat (IOA-289) clinical data in patients with pancreatic cancer at ESMO
Data & publication
The PI3Kδ inhibitor roginolisib (IOA-244) preserves T cell function and activity
Press release
iOnctura Expands Roginolisib Trials to the US, Advancing Multi-Indication Strategy in Oncology
Press coverage
Biotech TV – Interview with Catherine Pickering
Press coverage
OncLive – Early Activity With Roginolisib Supports Ongoing Phase 2 OCULE-01 Trial in Metastatic Uveal Melanoma
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